Waldemar Debinski Selected Research

Ephrin-A1 (Ephrin A1)

1/2021	Phase I trial of convection-enhanced delivery of IL13RA2 and EPHA2 receptor targeted cytotoxins in dogs with spontaneous intracranial gliomas.
6/2013	Biological and structural characterization of glycosylation on ephrin-A1, a preferred ligand for EphA2 receptor tyrosine kinase.
2/2012	Ephs and ephrins in cancer: ephrin-A1 signalling.

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Waldemar Debinski Research Topics

Disease

53	Neoplasms (Cancer) 01/2021 - 09/2002
35	Glioblastoma (Glioblastoma Multiforme) 01/2022 - 04/2005
21	Brain Neoplasms (Brain Tumor) 09/2021 - 01/2002
20	Glioma (Gliomas) 01/2022 - 09/2002
7	Breast Neoplasms (Breast Cancer) 11/2021 - 12/2007
6	Neoplasm Metastasis (Metastasis) 11/2021 - 09/2017
6	Astrocytoma (Pilocytic Astrocytoma) 01/2013 - 01/2002
3	Prostatic Neoplasms (Prostate Cancer) 12/2020 - 10/2013
3	Hypoxia (Hypoxemia) 01/2020 - 01/2009
3	Meningioma (Meningiomas) 01/2017 - 10/2012
2	Necrosis 01/2016 - 03/2014
1	Vesicular Stomatitis 09/2021
1	Renal Cell Carcinoma (Grawitz Tumor) 01/2018
1	Melanoma (Melanoma, Malignant) 08/2017
1	Choroid Plexus Neoplasms (Choroid Plexus Tumor) 01/2017
1	Heart Diseases (Heart Disease) 11/2016
1	Cognitive Dysfunction 11/2016
1	Lung Neoplasms (Lung Cancer) 01/2016

Drug/Important Bio-Agent (IBA)

16	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2002
13	Cytotoxins (Cytolysins)IBA 01/2021 - 01/2002
11	Interleukin-13IBA 01/2021 - 09/2002
11	LigandsIBA 05/2017 - 10/2005
9	Interleukin-13 Receptors (Interleukin 13 Receptor)IBA 01/2021 - 08/2003
8	Biomarkers (Surrogate Marker)IBA 12/2020 - 07/2005
8	Pharmaceutical PreparationsIBA 04/2020 - 01/2002
7	EphA2 ReceptorIBA 01/2021 - 12/2007
6	Transcription Factors (Transcription Factor)IBA 03/2021 - 03/2003
6	EphrinsIBA 01/2021 - 12/2008
5	Temozolomide (Temodar)FDA LinkGeneric 01/2022 - 04/2014
5	Eph Family Receptors (Eph Receptors)IBA 04/2020 - 12/2008
4	Biological ProductsIBA 10/2018 - 04/2005
4	Interleukin-13 Receptor alpha2 SubunitIBA 10/2008 - 11/2002
3	MicroRNAs (MicroRNA)IBA 11/2021 - 01/2018
3	Ephrin-A1 (Ephrin A1)IBA 01/2021 - 02/2012
3	AntigensIBA 04/2020 - 10/2013
3	AntibodiesIBA 01/2018 - 03/2003
3	Bacterial ToxinsIBA 08/2012 - 01/2002
3	fos-related antigen 1IBA 01/2011 - 04/2005
3	InterleukinsIBA 01/2009 - 07/2005
2	Glycoproteins (Glycoprotein)IBA 09/2021 - 11/2002
2	PT2385IBA 01/2020 - 01/2018
2	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 01/2018 - 01/2018
2	1-phenyl-3,3-dimethyltriazene (PDT)IBA 01/2018 - 01/2018
2	Photosensitizing Agents (Photosensitizers)IBA 01/2018 - 01/2018
2	Peptides (Polypeptides)IBA 08/2017 - 01/2012
2	Nuclear Localization Signals (Nuclear Localization Signal)IBA 05/2017 - 05/2010
2	ExotoxinsIBA 05/2017 - 08/2003
2	Glycosylphosphatidylinositols (Glycosyl-Phosphatidylinositol)IBA 01/2017 - 08/2012
2	EphA1 Receptor (Eph Receptor)IBA 09/2016 - 12/2014
2	Pseudomonas aeruginosa Exotoxin AIBA 10/2013 - 05/2010
2	Alanine (L-Alanine)FDA Link 04/2012 - 11/2002
2	Amino Acids FDA Link 04/2012 - 11/2002
2	Interleukin-4 (Interleukin 4)IBA 11/2007 - 09/2002
2	Vascular Endothelial Growth Factor DIBA 04/2005 - 03/2003
1	Green Fluorescent ProteinsIBA 09/2021
1	InterferonsIBA 09/2021
1	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2021
1	Epinephrine (Adrenaline)FDA LinkGeneric 12/2020
1	AndrogensIBA 12/2020
1	Hormones (Hormone)IBA 10/2020
1	Androgen Receptors (Androgen Receptor)IBA 10/2020
1	SteroidsIBA 10/2020
1	Androgen Antagonists (Antiandrogens)IBA 10/2020
1	Immune Checkpoint InhibitorsIBA 04/2020
1	endothelial PAS domain-containing protein 1IBA 01/2020
1	Antisense OligonucleotidesIBA 01/2020
1	RNA (Ribonucleic Acid)IBA 10/2019
1	ProdrugsIBA 10/2018
1	MethyltransferasesIBA 10/2018
1	liposomal doxorubicin (Doxil)FDA Link 01/2018
1	fludarabineIBA 01/2018
1	Long Noncoding RNAIBA 01/2018
1	XIST non-coding RNAIBA 01/2018
1	N2- (1H- indazole- 5- yl)- N6- methyl- 3- nitropyridine- 2,6- diamineIBA 09/2017
1	Copper-64IBA 08/2017
1	Cell Surface ReceptorsIBA 08/2017
1	Doxycycline (Periostat)FDA LinkGeneric 08/2017
1	Tumor Viral Antigens (Large T Antigen)IBA 05/2017
1	Doxorubicin (Adriamycin)FDA LinkGeneric 05/2017
1	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 01/2017
1	Caseins (Casein)FDA Link 01/2017
1	Plasminogen Activators (Plasminogen Activator)IBA 01/2017
1	PlasminogenIBA 01/2017
1	Messenger RNA (mRNA)IBA 01/2017
1	Urokinase Plasminogen Activator ReceptorsIBA 01/2017
1	EphB2 ReceptorIBA 09/2016
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 09/2016
1	Fluorouracil (Carac)FDA LinkGeneric 09/2016
1	serpentine (alkaloid)IBA 01/2016
1	Vascular Endothelial Growth Factor CIBA 09/2015

Therapy/Procedure

22	Therapeutics 09/2021 - 01/2008
5	Radiotherapy 01/2022 - 04/2014
3	Drug Therapy (Chemotherapy) 01/2022 - 10/2008
2	Chemoradiotherapy 01/2020 - 01/2016
2	Photochemotherapy (Photodynamic Therapy) 01/2018 - 01/2018
2	Catheters 12/2010 - 10/2009
1	Immunotherapy 04/2020
1	Craniotomy 10/2019
1	Aftercare (After-Treatment) 08/2017
1	Precision Medicine 01/2016